Megaesophagus in a Patient with Achalasia

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Megaesophagus in a line of transgenic rats: a model of achalasia.

Megaesophagus is defined as the abnormal enlargement or dilatation of the esophagus, characterized by a lack of normal contraction of the esophageal walls. This is called achalasia when associated with reduced or no relaxation of the lower esophageal sphincter (LES). To date, there are few naturally occurring models for this disease. A colony of transgenic (Pvrl3-Cre) rats presented with megaes...

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ژورنال

عنوان ژورنال: GE - Portuguese Journal of Gastroenterology

سال: 2018

ISSN: 2341-4545,2387-1954

DOI: 10.1159/000487276